Cancer-directed surgery in malignant pleural mesothelioma: extrapleural pneumonectomy and pleurectomy/decortication

Malignant pleural mesothelioma (MPM) is a primary solid malignancy related to inhalational asbestos exposure. Despite advances in therapy, MPM remains challenging treat with post-treatment survival of only 15% at 5-year. In recent years, extra-pleural pneumonectomy has decreased popularity due high morbidity rate and mortality compared pleurectomy/decortication other therapeutic alternatives. this review, we will discuss both procedures, outcomes, ongoing studies, the roles surgery future treatment disease.